A new site for mycobacterial ATP synthase plays a new role
The ATP synthase of many anaerobic archaea have the unusual motor subunit c, otherwise only found in eukaryotic V1VO ATPases. The evolutionary transition from synthase to hydrolase is thought to be caused by the doubling of the rotor subunit c, followed by the loss of an ion-binding site. By purifying and reconstituting an ATP synthase with a …
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